How does Salvia affect the brain?
Carmela Pellegrino
2025-04-17 08:25:12
Numero di risposte: 1
Salvia divinorum increases the communication across parts of the brain.
Salvinorin A results in more random or disconnected signaling within the default mode network, which is the part of the brain most active when a person is sitting still, relaxing, daydreaming or otherwise not engaged in externally directed mental exercise.
Salvinorin A produces powerful out-of-body and amnesia-like experiences over a short time frame similar to the effects of nitrous oxide.
Most of the fMRI-scanned networks seemed to communicate more with one another when influenced by salvinorin A than when the drug was not present, but they communicated less within themselves.
The researchers observed particularly decreased synchronization of the default mode network, meaning that the brain’s electrical signals became more random and unpredictable.
Elsa Ferrara
2025-04-17 07:04:13
Numero di risposte: 1
Salvinorin A, salvia’s active ingredient, impacts the brain in unclear ways. It’s thought that this ingredient attaches to the nerve cells in your body to create a variety of hallucinogenic effects. The effects of salvia on your brain may include visual and auditory hallucinations, such as seeing bright lights, vivid colors, or extreme shapes.
Other effects include distorted reality and altered perceptions of surroundings, as well as feeling as if you’re having an “out-of-body” experience or feeling detached from reality. Some people may also experience slurred speech, laughing uncontrollably, or anxiety from a “bad trip.”
A 2011 animal study found that salvia use may have negative effects on learning and impair long-term memories. These effects may occur rapidly, within just 5 to 10 minutes of smoking or inhaling the drug.
Vittorio Carbone
2025-04-17 06:41:36
Numero di risposte: 1
Salvia divinorum's active component, salvinorin A, travels through the brain extremely fast, peaking within 40 seconds of administration—nearly 10 times faster than cocaine.
High concentrations of the drug localize to the cerebellum and visual cortex, affecting motor function and vision.
The effects described by users include an almost immediate high that starts fading within 5–10 minutes, distinguishing it from other hallucinogens due to its rapid onset and short duration.
Unlike LSD, Salvia doesn't typically induce euphoria but targets receptors that modulate pain and may have therapeutic potential for mood disorders.
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